abstract：:Acute irritant contact dermatitis (ICD) is frequently treated with cool water or saline compresses. While presumed effective, little quantitative evaluation documents the treatment's benefit. This study sought to determine the efficacy of both distilled water and physiologic saline compresses on experimentally-induced...

journal_title：Contact dermatitis

authors： Levin CY,Maibach HI

更新日期：2001-09-01 00:00:00

abstract：:The validity of questionnaire answers with respect to hand eczema was investigated. Car mechanics, dentists and office workers answered a questionnaire on the occurrence of hand eczema on any occasion during the past 12 months. "Yes"-responders and a random sample of "no"-responders were subsequently interviewed and e...

journal_title：Contact dermatitis

authors： Meding B,Barregård L

更新日期：2001-08-01 00:00:00

abstract：:For more than 50 years, the Draize rabbit skin irritation test has reigned supreme as the regulatory method of choice for the identification of skin irritant chemicals. To date no in vitro alternative test has been validated as an adequate replacement. However, one potential option, to test the endpoint of concern (sk...

journal_title：Contact dermatitis

authors： Robinson MK,McFadden JP,Basketter DA

更新日期：2001-07-01 00:00:00

abstract：:The new Dangerous Preparations Directive (DPD, 1999/45/EC) introduces a special labelling requirement for skin sensitizers in products that are regulated under this Directive. The packaging of products containing 0.1% of a sensitizer must bear the inscription "Contains 'name of sensitizer'. May produce an allergic rea...

journal_title：Contact dermatitis

authors： Roggeband R,Basketter DA,De Groot AC,Robinson MK,Gerberick GF

更新日期：2001-06-01 00:00:00

abstract：:118 consecutive patients were photopatch tested with 5J UVA and 10mJ UVB. In addition, day 7 readings were taken. Testing with UVB and performing late readings conferred no advantage. The current recommendations of the British Photodermatology Group regarding photopatch testing remain the most recent guide to photopat...

journal_title：Contact dermatitis

authors： Pollock B,Wilkinson SM

更新日期：2001-05-01 00:00:00

abstract：:The aim of the study was to assess occupational hazards to the farmer's skin associated with processing thyme (Thymus vulgaris L.). 46 farmers were studied during the threshing of dried thyme. They were questioned about work-related skin problems and examined before and after work. In all persons, serum thyme-specific...

journal_title：Contact dermatitis

authors： Spiewak R,Skorska C,Dutkiewicz J

更新日期：2001-04-01 00:00:00

abstract：:Between 1995 and 1999, 1986 patients were tested in the 31 participating centres of the Information Network of Departments of Dermatology (IVDK), all of them members of the German Contact Dermatitis Research Group, with a textile dyes series containing Disperse Blue (DB) 106 and 124, and since 1997 also with a mix of ...

journal_title：Contact dermatitis

authors： Uter W,Geier J,Lessmann H,Hausen BM,IVDK and the German Contact Dermatitis Research Grooup. Information Network of Departments of Dermatology.

更新日期：2001-03-01 00:00:00

abstract：:This is a study of occupational skin disease among military personnel and conscripts in Singapore. All military personnel and conscripts diagnosed with occupational dermatoses in the National Skin Centre, Singapore, between 1989-1999 were studied retrospectively. Conscripts and regulars comprised 7.3% of all occupatio...

journal_title：Contact dermatitis

authors： Goon AT,Goh CL

更新日期：2001-02-01 00:00:00

abstract：:We review controlled trials of corticosteroid effect in experimentally elicited acute nickel contact dermatitis in man, in the hope of clarifying optimal efficacy for clinical use. To maximize discrimination and objectivity, we focus on data with 1 well-characterized allergen, nickel, in studies utilizing bioengineeri...

journal_title：Contact dermatitis

authors： Levin C,Maibach HI

更新日期：2000-12-01 00:00:00

abstract：:Effects of test techniques on neomycin patch test results have not been thoroughly investigated. This study focuses on effects of dose and application time of neomycin sulfate patch tests on test results. The effects are assessed both visually and by perfusion. 16 subjects positive to neomycin are retested with neomyc...

journal_title：Contact dermatitis

authors： Bjarnason B,Flosadóttir E

更新日期：2000-11-01 00:00:00

abstract：:The present study aimed at evaluating the effects of daily repeated exposures to low cobalt or chromate concentrations on the hands of patients with hand eczema and cobalt or chromate allergy. For 2 weeks, the patients immersed a finger for 10 min daily into the appropriate metal salt solution in water. During the 1st...

journal_title：Contact dermatitis

authors： Nielsen NH,Kristiansen J,Borg L,Christensen JM,Poulsen LK,Menné T

更新日期：2000-10-01 00:00:00

abstract：:The possible interference of neighbouring allergic patch-test reactions is still an open question. In this study, we investigated whether there is a distance-related mutual modification of neighbouring allergic patch-test reactions to nickel sulfate and potassium dichromate. We used a double-blind multicentre study de...

journal_title：Contact dermatitis

authors： Brasch J,Kreilgård B,Henseler T,Aberer W,Fuchs T,Pflüger R,Hoeck U,Gefeller O

更新日期：2000-09-01 00:00:00

abstract：:We report the results of patch tests with fragrance-mix as a part of the standard series carried out over the last 10 years (1989-1998) during routine testing of 6129 patients in our department. 5.9% of the total number of patients who were patch tested were positive to fragrance mix. The sex ratio was 2.3:1 with a fe...

journal_title：Contact dermatitis

authors： Lunder T,Kansky A

更新日期：2000-08-01 00:00:00

abstract：:As one step in defining the clinical relevance of exposure to an allergen identified with patch testing, use tests (provocative use test (PUT), and repeated open application test (ROAT)) have been used. In 1/2 of the cases of seemingly reliable patch tests, use tests are negative, suggesting that the patient's biologi...

journal_title：Contact dermatitis

authors： Nakada T,Hostynek JJ,Maibach HI

更新日期：2000-07-01 00:00:00

abstract：:Chronic irritant contact dermatitis (ICD) is a common skin disease, especially in the workplace, but determining the recovery time of chronic ICD is not easy. To measure the recovery time of chronic ICD, we examined the skin reactivity to a model surfactant, sodium lauryl sulfate (SLS), on previous chronic ICD and nor...

journal_title：Contact dermatitis

authors： Choi JM,Lee JY,Cho BK

更新日期：2000-05-01 00:00:00

abstract：:In this study, the applicability of a symptom-based questionnaire on hand dermatitis was assessed in a population of rubber workers. The questionnaire was previously validated in a study among nurses. 224 subjects employed in 9 different companies completed a questionnaire on skin complaints. Subsequently, 202 workers...

journal_title：Contact dermatitis

authors： Vermeulen R,Kromhout H,Bruynzeel DP,de Boer EM

更新日期：2000-04-01 00:00:00

abstract：:Quercetin is a bioflavonoid with antioxidant and anti-inflammatory activity. The purpose of this study was to examine the effect of quercetin on acute skin irritation, with special interest in the skin barrier function recovery. Acute irritant contact dermatitis was induced in 15 patients by 24-h occlusion of 2% sodiu...

journal_title：Contact dermatitis

authors： Katsarou A,Davoy E,Xenos K,Armenaka M,Theoharides TC

更新日期：2000-02-01 00:00:00

abstract：:Interleukin-12 (IL-12) has previously been suggested as playing a major rôle in the activation of cytotoxic lymphocytes. Recent reports indicate that cytotoxic CD8+ cells are critically involved in the elicitation phase of contact hypersensitivity reactions. In this study, the in situ expression of IL-12 was investiga...

journal_title：Contact dermatitis

authors： Yawalkar N,Egli F,Brand CU,Pichler WJ,Braathen LR

更新日期：2000-01-01 00:00:00

abstract：:Water is a skin irritant which deserves attention because of its ubiquity. During the Vietnam war, soldiers suffered from painful swollen feet, so-called tropical immersion foot. In occupational dermatology, the importance of water as a skin irritant is especially appreciated. The irritancy of water has been demonstra...

journal_title：Contact dermatitis

authors： Tsai TF,Maibach HI

更新日期：1999-12-01 00:00:00

abstract：:Patch testing is an invaluable tool for the experimental induction of acute irritant contact dermatitis (ICD), with a variety of chamber systems available for use. Ideally, the inflammatory reactions produced should be of uniform intensity across the test area, thereby facilitating grading of the response and tissue s...

journal_title：Contact dermatitis

authors： Nicholson M,Willis CM

更新日期：1999-11-01 00:00:00

abstract：:Patch-test technique for budesonide needs improvement. 20 subjects with positive or questionable patch-test responses to budesonide were retested for 3 to 96 h (4 days [D]) with polyester patches coated with budesonide in serial doses (150 to 0.074 microg/cm2). Multiple readings were taken visually and with a laser Do...

journal_title：Contact dermatitis

authors： Bjarnason B,Flosadóttir E,Fischer T

更新日期：1999-10-01 00:00:00

abstract：:A healed or healing allergic contact dermatitis is easily reactivated to a flare-up if the patient is provoked systemically with his particular allergen. 5 patients with contact allergy to gold were patch tested with a serial dilution of gold sodium thiosulfate. 1 to 2 months later, when positive test reactions were h...

journal_title：Contact dermatitis

authors： Möller H,Björkner B,Bruze M,Lundqvist K,Wollmer P

更新日期：1999-09-01 00:00:00

abstract：:The laser Doppler perfusion scanning technique is an objective, non-invasive assessment method that may be used to assess patch tests. The purpose of this paper is to focus on its clinical use in individuals with light skin, tested with non-pigmented test materials. A laser Doppler perfusion imager PIM 1.0 (LDPI) is u...

journal_title：Contact dermatitis

authors： Bjarnason B,Flosadóttir E,Fischer T

更新日期：1999-05-01 00:00:00

abstract：:Exaggerated test conditions were frequently used to investigate the cutaneous tolerance of detergent products in the past. As the sensitivity of newly designed biometric methods is steadily improving, the trend towards more realistic test conditions should be encouraged. A hand immersion test under laboratory-controll...

journal_title：Contact dermatitis

authors： Paye M,Gomes G,Zerweck CR,Piérard GE,Grove GL

更新日期：1999-03-01 00:00:00

abstract：:To test the screening value of the sesquiterpene lactone (SL) mix in Europe today and describe epidemiological and clinical features of Compositae-sensitive patients, the SL mix 0.1% pet. was included in the standard patch test series in 11 European clinics. 10,695 patients were tested, and 106 (1%) had positive react...

journal_title：Contact dermatitis

authors： Paulsen E,Andersen KE,Brandão FM,Bruynzeel DP,Ducombs G,Frosch PJ,Goossens A,Lahti A,Menné T,Shaw S,Tosti A,Wahlberg JE,Wilkinson JD,Wrangsjö K

更新日期：1999-02-01 00:00:00

abstract：:Some methacrylates are known to be strong contact sensitizers. To determine the effect of side-chain length on sensitizing potential, we examined 11 derivatives with linear side chains from C1 to C18 in an experimental sensitization test in guinea pigs. The results showed an increase in the sensitizing potential with ...

journal_title：Contact dermatitis

authors： Kanazawa Y,Yoshida T,Kojima K

更新日期：1999-01-01 00:00:00

abstract：:Deodorants are one of the most frequently-used types of cosmetics and are a source of allergic contact dermatitis. Therefore, a gas chromatography - mass spectrometric analysis of 71 deodorants was performed for identification of fragrance and non-fragrance materials present in marketed deodorants. Futhermore, the sen...

journal_title：Contact dermatitis

authors： Rastogi SC,Lepoittevin JP,Johansen JD,Frosch PJ,Menné T,Bruze M,Dreier B,Andersen KE,White IR

更新日期：1998-12-01 00:00:00

abstract：:In this study of 152 women, comparison of patch test responses between 2 irritants over 96 h at 2 symmetrical anatomical sites is studied. 2 irritants, each at 4 different concentrations (nonanoic acid (NAA) 80%, 40%, 20%, 10%; sodium lauryl sulfate (SLS) 3%, 2%, 1% and 0.5%) and using propan-1ol and 'water for inject...

journal_title：Contact dermatitis

authors： Reiche L,Willis C,Wilkinson J,Shaw S,de Lacharrière O

更新日期：1998-11-01 00:00:00

abstract：:Deodorants are one of the most marketed types of cosmetics and are frequently reported as a cause of dermatitis, particularly among fragrance-sensitive persons. The aim of this study was to investigate the ability of deodorants, which had previously caused axillary dermatitis in fragrance-mix-sensitive eczema patients...

journal_title：Contact dermatitis

authors： Johansen JD,Rastogi SC,Bruze M,Andersen KE,Frosch P,Dreier B,Lepoittevin JP,White I,Menné T

更新日期：1998-10-01 00:00:00

abstract：:2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) is an azo compound which has been used as a radical chain initiator. The purpose of this study was to confirm contact sensitivity to AAPH in individuals who were engaged in the production of AAPH, and presented with prolonged eczematous eruptions mainly on exposed a...

journal_title：Contact dermatitis

authors： Takiwaki H,Arase S,Nakayama H

更新日期：1998-07-01 00:00:00

abstract：:Protein kinase C (PKC) isoforms are important in cell signal transduction associated with regulation of cell proliferation and differentiation. In this study, alterations of PKC isoform levels in irritant patch test reactions were detected by Western immunoblots. 4 chemically and structurally different irritants, 4% a...

journal_title：Contact dermatitis

authors： Li LF,Fiedler VC,Kumar R

更新日期：1998-06-01 00:00:00

abstract：:The arylpropionic acid derivatives (APADs) ketoprofen and tiaprofenic acid can provoke photoallergic dermatitis. Possible cross-reactivity between APADs is of importance in patients using nonsteroidal anti-inflammatory drugs. Because of the similarities in chemical structures, we investigated patients with photoallerg...

journal_title：Contact dermatitis

authors： Le Coz CJ,Bottlaender A,Scrivener JN,Santinelli F,Cribier BJ,Heid E,Grosshans EM

更新日期：1998-05-01 00:00:00

abstract：:A human 4-h patch test has recently been developed for testing the irritation hazard potential of chemicals. The original method was developed for comparative irritation assessments relative to benchmark irritants using simple statistical tests. In this context, the method has been shown to be robust in intralaborator...

journal_title：Contact dermatitis

authors： Robinson MK,Perkins MA,Basketter DA

更新日期：1998-04-01 00:00:00

abstract：:A cohort of initially 111 office apprentices was prospectively followed for the duration of their training (2 and 3 years, respectively). The point prevalence of (slight) irritant or atopic hand eczema was 18.9% in the initial and 25.0% in the final examinations. Altogether, 37 cases of (slight) hand eczema were noted...

journal_title：Contact dermatitis

authors： Uter W,Pfahlberg A,Gefeller O,Schwanitz HJ

更新日期：1998-02-01 00:00:00

abstract：:Exposure to formaldehyde is common from both consumer products and industry. The reliability of the patch test is essential for the diagnosis of formaldehyde allergy as it is difficult to suspect from the patient's history. The recommended formaldehyde patch test concentration has been reduced over the last decades fr...

journal_title：Contact dermatitis

authors： Trattner A,Johansen JD,Menné T

更新日期：1998-01-01 00:00:00

abstract：:Cocamidopropyl betaine (CAPB) is an amphoteric surfactant commonly used in personal care products and surface cleaners. Patch testing with commercially-available CAPB has yielded occasional reactions indicative of allergic contact dermatitis. To determine if subjects with previous positive patch tests would react in p...

journal_title：Contact dermatitis

authors： Fowler JF,Fowler LM,Hunter JE

更新日期：1997-12-01 00:00:00

abstract：:This review summarizes published and unpublished data of our 15-year experience with sunscreen allergy and photoallergy. From 1981-1996, 402 patients with suspected clinical photosensitivity were patch and photopatch tested with the commercial sunscreens and facial cosmetics that they had used and with chemical UV abs...

journal_title：Contact dermatitis

authors： Schauder S,Ippen H

更新日期：1997-11-01 00:00:00

abstract：:It has been known since the 1940s that nail polishes contain allergenic ingredients. The aim of this study was to clarify whether the nail polishes on the market today contain significant amounts of allergens, and what the solvents are. The following ingredients were determined: toluene, toluene sulfonamide formaldehy...

journal_title：Contact dermatitis

authors： Sainio EL,Engström K,Henriks-Eckerman ML,Kanerva L

更新日期：1997-10-01 00:00:00

abstract：:The low-molecular-weight phenols 2-methylol phenol (2-MP), 4-methylol phenol (4-MP), 2,4,6-trimethylol phenol (2,4,6-MP), 3-methylol phenol (3-MP), 2,4-dimethylol phenol (2,4-MP), and 2,6-dimethylol phenol (2,6-MP) are contact sensitizers in resins based on phenol and formaldehyde (P-F-R). Other chemically related low...

journal_title：Contact dermatitis

authors： Bruze M,Zimerson E

更新日期：1997-08-01 00:00:00

abstract：:Tween 80 is an ethoxylated hydrophilic non-ionic surfactant, which is used for the preparation of oil-in-water emulsions in pharmaceutical products, cosmetics, and industrial detergents. Ethoxylated surfactants are polyethers and are thus easily oxidized by atmospheric oxygen to a variety of hydroperoxides, peroxides ...

journal_title：Contact dermatitis

authors： Bergh M,Magnusson K,Nilsson JL,Karlberg AT

更新日期：1997-07-01 00:00:00